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pak-li-TAX-el PROE-teen - bownd

Intravenous route(Powder for Suspension)

Paclitaxel protein-bound particles therapy should not be administered to patients with metastatic breast cancer who have baseline neutrophil counts of less than 1500 cells/mm(3). It is recommended that frequent peripheral blood cell counts be performed on all patients in order to monitor for the occurrence of bone marrow suppression. An albumin form of paclitaxel may substantially affect a drug's functional properties relative to those of drug in solution. Do not substitute for or with other paclitaxel formulations .

Commonly used brand name(s)

In the U.S.

  • Abraxane

Available Dosage Forms:

  • Powder for Suspension

Therapeutic Class: Antineoplastic Agent

Pharmacologic Class: Mitotic Inhibitor

Uses For paclitaxel protein-bound

Paclitaxel protein-bound belongs to the group of medicines called antineoplastics. It is used to treat cancer of the breast after other treatments have failed.

Paclitaxel interferes with the growth of cancer cells, which are eventually destroyed. Since the growth of normal body cells may also be affected by paclitaxel protein-bound, other effects will also occur. Some of these may be serious and must be reported to your doctor. Other effects may not be serious but may cause concern. Some effects may not occur until months or years after the medicine is used.

Before you begin treatment with paclitaxel protein-bound, you and your doctor should talk about the good paclitaxel protein-bound will do as well as the risks of using it.

paclitaxel protein-bound is available only with your doctor's prescription.

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although these uses are not i

levonorgestrel
Dosage Form: tablet
FULL PRESCRIBING INFORMATION

Indications and Usage for Plan B

Plan B® One-Step is a progestin-only emergency contraceptive indicated for prevention of pregnancy following unprotected intercourse or a known or suspected contraceptive failure. To obtain optimal efficacy, the tablet should be taken as soon as possible within 72 hours of intercourse.

Plan B One-Step is available only by prescription for women younger than age 17 years, and available over the counter for women 17 years and older.

Plan B One-Step is not indicated for routine use as a contraceptive.

Plan B Dosage and Administration

Take Plan B One-Step orally as soon as possible within 72 hours after unprotected intercourse or a known or suspected contraceptive failure. Efficacy is better if the tablet is taken as soon as possible after unprotected intercourse. Plan B One-Step can be used at any time during the menstrual cycle.

If vomiting occurs within two hours of taking the tablet, consideration should be given to repeating the dose.

Dosage Forms and Strengths

The Plan B One-Step tablet is supplied as an almost white, round tablet containing 1.5 mg of levonorgestrel and is marked G00 on one side.

Contraindications

Plan B One-Step is contraindicated for use in the case of known or suspected pregnancy.

Generic Name: phenylephrine hydrochloride
Dosage Form: ophthalmic solution
Phenylephrine Hydrochloride Ophthalmic Solution, 2.5%
Vasoconstrictor and Mydriatic
For Use in Ophthalmology

WARNING:

PHYSICIANS SHOULD COMPLETELY FAMILIARIZE THEMSELVES WITH THE COMPLETE CONTENTS OF THIS LEAFLET BEFORE PRESCRIBING PHENYLEPHRINE HYDROCHLORIDE.

Phenylephrine Ophthalmic Solution Description

Phenylephrine Hydrochloride Ophthalmic Solution, 2.5% is a sterile topical ophthalmic solution. The active ingredient is represented by the chemical structure:

Chemical name: Benzenemethanol,3-hydroxy-?-[(methylamino)methyl]-,hydrochloride (R)-.
Established name: Phenylephrine Hydrochloride

Each mL contains: Active: Phenylephrine HCl 2.5%. Preservative: Benzalkonium Chloride 0.01%. Inactive: Boric Acid, Sodium Bisulfite, Edetate Disodium, Sodium Hydroxide and/or Hydrochloric Acid (to adjust pH), Purified Water.

Phenylephrine Ophthalmic Solution - Clinical Pharmacology

Phenylephrine HCl is an alpha receptor sympathetic agonist used in local ocular disorders because of its vasoconstrictor and mydriatic action. It exhibits rapid and moderately prolonged action, and it produces little rebound vasodilation. Systemic side effects are uncommon.

Generic Name: fluoxetine hydrochloride
Dosage Form: capsule
FULL PRESCRIBING INFORMATION
WARNING: SUICIDALITY AND ANTIDEPRESSANT DRUGS

Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents, and young adults in short-term studies of Major Depressive Disorder (MDD) and other psychiatric disorders. Anyone considering the use of PROZAC or any other antidepressant in a child, adolescent, or young adult must balance this risk with the clinical need. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction in risk with antidepressants compared to placebo in adults aged 65 and older. Depression and certain other psychiatric disorders are themselves associated with increases in the risk of suicide. Patients of all ages who are started on antidepressant therapy should be monitored appropriately and observed closely for clinical worsening, suicidality, or unusual changes in behavior. Families and caregivers should be advised of the need for close observation and communication with the prescriber. PROZAC is approved for use in pediatric patients with MDD and Obsessive Compulsive Disorder (OCD) [see Warnings and Precautions (5.1) and Use in Specific Populations (8.4)].

When using PROZAC and olanzapine in combination, also refer to Boxed Warning section of the package insert for Symbyax.

Pronunciation: POE-vi-done/EYE-oh-dine
Generic Name: Povidone/Iodine
Brand Name: Examples include Betadine and Operand

Povidone/Iodine Douche is used for:

Relieving minor vaginal irritation and itching. It may also be used to cleanse and deodorize the vaginal area.

Povidone/Iodine Douche is an antiseptic combination. It works by killing sensitive bacteria.

Do NOT use Povidone/Iodine Douche if:

  • you are allergic to any ingredient in Povidone/Iodine Douche
  • you are pregnant or breast-feeding

Contact your doctor or health care provider right away if any of these apply to you.

Before using Povidone/Iodine Douche:

Some medical conditions may interact with Povidone/Iodine Douche. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are planning to become pregnant
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have pelvic inflammatory disease (PID), a history of sexually transmitted diseases (STDs), or thyroid problems

Some MEDICINES MAY INTERACT with Povidone/Iodine Douche. However, no specific interactions are known at this time.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Povidone/Iodine Douche may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use P

Pronunciation: pra-MOX-een
Generic Name: Pramoxine
Brand Name: Proctofoam

Proctofoam Foam is used for:

Treating pain, soreness, burning, and itching of the anal area due to hemorrhoids.

Proctofoam Foam is a topical anesthetic. It works by blocking pain signals from the nerve endings in the skin. This helps relieve discomfort.

Do NOT use Proctofoam Foam if:

  • you are allergic to any ingredient in Proctofoam Foam

Contact your doctor or health care provider right away if any of these apply to you.

Before using Proctofoam Foam:

Some medical conditions may interact with Proctofoam Foam. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Proctofoam Foam. Because little, if any, of Proctofoam Foam is absorbed into the blood, the risk of it interacting with another medicine is low.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Proctofoam Foam may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Proctofoam Foam:

Use Proctofoam Foam as directed by your doctor. Check the label on the medicine for exact dosing instructions.

    Pronunciation: ox-i-TOE-sin
    Generic Name: Oxytocin
    Brand Name: Pitocin

    Pitocin is used for:

    Inducing labor in women with Rh problems, diabetes, preeclampsia, or when it is in the best interest of the mother or fetus. It is also used to help abort the fetus in cases of incomplete abortion or miscarriage, produce contractions during the third stage of labor, and control bleeding after childbirth.

    Pitocin is a uterine stimulant. It works by causing uterine contractions by changing calcium concentrations in the uterine muscle cells.

    Do NOT use Pitocin if:

    • you are allergic to any ingredient in Pitocin
    • your birth canal is too small compared with the fetus's head
    • the fetus is in a difficult position within the womb or is in distress and delivery is not progressing
    • you have other complications that require medical intervention for birth
    • you have bacteria in the blood
    • you cannot have a child through vaginal delivery because of certain conditions (eg, genital herpes, cervical cancer)

    Contact your doctor or health care provider right away if any of these apply to you.

    Before using Pitocin:

    Some medical conditions may interact with Pitocin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

    • if you are breast-feeding
    • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
    • if you have allergies to medicines, fo
    Pronunciation: fen-AY-zoe-PIR-i-deen/BUE-ta-BAR-bi-tal/HYE-oh-SYE-a-meen
    Generic Name: Phenazopyridine/Butabarbital/Hyoscyamine
    Brand Name: Examples include PhenazoForte Plus and Urelief Plus

    Phenazopyridine/Butabarbital/Hyoscyamine is used for:

    Relieving pain, burning, urgency, frequent urination, and discomfort caused by irritation of the lower urinary tract. It may also be used for other conditions as determined by your doctor.

    Phenazopyridine/Butabarbital/Hyoscyamine is an analgesic, anticholinergic, and antianxiety combination. It works by decreasing the motion of muscles in the stomach, intestines, and bladder. It also decreases the production of stomach acid.

    Do NOT use Phenazopyridine/Butabarbital/Hyoscyamine if:

    • you are allergic to any ingredient in Phenazopyridine/Butabarbital/Hyoscyamine
    • you have the blood disease porphyria; decreased liver or kidney function; severe esophagus problems (eg, irritation, narrowing); a blockage of the stomach, bowel, or bladder; bowel motility problems; or severe bowel problems (eg, severe ulcerative colitis, toxic megacolon)
    • you have glaucoma, myasthenia gravis, or heart problems caused by severe bleeding
    • you are taking sodium oxybate (GHB)

    Contact your doctor or health care provider right away if any of these apply to you.

    Before using Phenazopyridine/Butabarbital/Hyoscyamine:

    Some medical conditions may interact with Phenazopyridine/Butabarbital/Hyoscyamine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

    • if you are pregnant, planning to become
    Pronunciation: DEX-troe-meth-OR-fan/poe-TASS-ee-um gywe-a-kole-SUL-foe-nate
    Generic Name: Dextromethorphan/Potassium Guaiacolsulfonate
    Brand Name: Examples include Guiadex DM and Prolex DM

    Prolex DM is used for:

    Temporarily relieving cough due to minor throat and airway irritation associated with upper respiratory tract infections or inhaled irritants.

    Prolex DM is a combination of an expectorant and a cough suppressant. It works by loosening mucus and lung secretions in the chest and making coughs more productive.

    Do NOT use Prolex DM if:

    • you are allergic to any ingredient in Prolex DM
    • you have taken a monoamine oxidase (MAO) inhibitor (eg, selegiline) within the last 14 days
    • you are taking a selective serotonin reuptake inhibitor (SSRI) (eg, fluoxetine)

    Contact your doctor or health care provider right away if any of these apply to you.

    Before using Prolex DM:

    Some medical conditions may interact with Prolex DM. Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

    • if you are pregnant, plan to become pregnant, or are breast-feeding
    • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
    • if you have allergies to medicines, foods, or other substances
    • if you have chronic cough, chronic bronchitis, or any breathing problems, such as asthma, emphysema, or chronic obstructive pulmonary disease (COPD)

    Some MEDICINES MAY INTERACT with Prolex DM. Tell your heal

    Generic Name: finasteride (fih NAH steh ride)
    Brand Names: Propecia, Proscar

    What is finasteride?

    Finasteride prevents the conversion of testosterone to dihydrotestosterone (DHT) in the body. DHT is involved in the development of benign prostatic hyperplasia (BPH).

    Finasteride is used to treat male pattern hair loss in men. It is also used to treat symptoms of benign prostatic hyperplasia (BPH) in men with an enlarged prostate.

    Finasteride may also be used for purposes not listed in this medication guide.

    What is the most important information I should know about finasteride?

    Finasteride should never be taken by a woman or a child. Finasteride can be absorbed through the skin, and women or children should not be permitted to handle finasteride tablets. Although finasteride is not for use by women, this medication can cause birth defects if a woman is exposed to it during pregnancy. Finasteride tablets should not be handled by a woman who is pregnant or who may become pregnant. If a woman accidentally comes into contact with this medication from a broken or crushed tablet, wash the area with soap and water right away. Before taking finasteride, tell your doctor if you have ever had an allergic reaction to this medication, or to a similar medicine called dutasteride (Avodart).

    Using finasteride may increase your risk of developing prostate cancer. Your doctor will perform tests to make sure you do not have other conditions that would prevent you from safely using finasteride.

    Call your doctor at once if you notice any breast lumps, pain, nipple discharge, or other breast changes. These may be signs of male

    Dosage Form: gel, dentifrice
    Colgate®
    PreviDent® 5000 ppm
    ENAMEL PROTECT

    Rx ONLY

    1.1% Sodium Fluoride, 5% Potassium Nitrate

    Prescription Strength Toothpaste For Sensitive Teeth

    Prevident 5000 Enamel Protect Description

    Self-topical neutral fluoride toothpaste containing 1.1% (w/w) sodium fluoride and 5% potassium nitrate.

    Active Ingredients

    Sodium fluoride 1.1% (w/w), Potassium nitrate 5%

    Inactive Ingredients

    water, hydrated silica, sorbitol, PEG-12, carrageenan, sodium lauryl sulfate, flavor, poloxamer 407, titanium dioxide, cocamidopropyl betaine, sodium saccharin, sodium hydroxide

    Prevident 5000 Enamel Protect - Clinical Pharmacology

    Frequent topical applications to the teeth with preparations having a relatively high fluoride content increase tooth resistance to acid dissolution and enhance penetration of the fluoride ion into tooth enamel.

    Indications and Usage for Prevident 5000 Enamel Protect

    A dental caries preventive and sensitive teeth toothpaste; for twice daily self-applied topical use, followed by rinsing. Helps reduce the painful sensitivity of the teeth to cold, heat, acids, sweets or contact in adult patients and children 12 years of age and older. It is well established that 1.1% sodium fluoride is safe and extraordinarily effective as a caries preventive when applied frequently with mouthpiece applicators.1-4 PreviDent® 5000 Enamel Protect brand of 1.1% sodium fluoride toothpaste with 5% potassium nitrate in a squeeze bottle is easily applied onto a toothbrush. This prescription toothpaste should be used twice daily in place of your regular toothpast

    Generic Name: guaifenesin/phenylephrine/phenylpropanolamine (gwye FEN e sin/fen ill EFF rin/fen ill proe pa NOLE a meen)
    Brand Names: Ami-Tex, Banex, Dura-Gest, Duratex, Enomine, Entex, Fentex, Guaifenex, Phenylfenesin, Quintex

    What is Phenylfenesin (guaifenesin/phenylephrine/phenylpropanolamine)?

    Guaifenesin is an expectorant. It is used to break up congestion and mucous to ease breathing. Guaifenesin thins mucous, increases lubrication of the respiratory tract (lungs, nose, and throat), and increases the removal of mucous.

    Phenylpropanolamine and phenylephrine are decongestants. They constrict (shrink) blood vessels (veins and arteries), which reduces the swelling of mucous membranes in areas such as the nose and sinuses.

    Guaifenesin/phenylephrine/phenylpropanolamine is used to treat the symptoms of the common cold and of infections of your sinuses, your lungs, and your throat.

    Phenylpropanolamine, an ingredient in this product, has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends that consumers not use any products that contain phenylpropanolamine.

    Guaifenesin/phenylephrine/phenylpropanolamine may also be used for purposes other than those listed in this medication guide.

    What is the most important information I should know about Phenylfenesin (guaifenesin/phenylephrine/phenylpropanolamine)?

    Phenylpropanolamine, an ingredient in this product, has been associated with an increased risk of hemorrhagic stroke (bleeding into the brain or into tissue surrounding the brain) in women. Men may also be at risk. Although the risk of hemorrhagic stroke is low, the U.S. Food and Drug Administration (FDA) recommends

    Generic Name: bismuth subcitrate, metronidazole, and tetracycline (Oral route)

    BIZ-muth sub-SIT-rate poe-TAS-ee-um, met-roe-NYE-da-zole, tet-ra-SYE-kleen hye-droe-KLOR-ide

    Oral route(Kit)

    Metronidazole has been shown to be carcinogenic in mice and rats. Unnecessary use of the drug should be avoided .

    Commonly used brand name(s)

    In the U.S.

    • Pylera

    Available Dosage Forms:

    • Capsule

    Therapeutic Class: Antiulcer, Helicobacter Pylori

    Chemical Class: Nitroimidazole

    Uses For Pylera

    Bismuth subcitrate, metronidazole, and tetracycline are combined in a single capsule that is used together with omeprazole to treat a stomach infection caused by the H. pylori bacteria. This bacteria can cause stomach ulcers if it is not treated. This medicine should not be used for any other infection .

    This medicine is available only with your doctor's prescription .

    Before Using Pylera

    In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

    Allergies

    Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

    Pediatric

    Because of tetracycline's toxicity, use in children younger than 8 years of age is not recommended. Tetracycline may cause permanent discoloration of the teeth. Safety and efficacy have not been established in this age group .

    Geriatric

    Appropriate studies performed


    Dosage Form: ophthalmic solution
    Polytrim®
    (polymyxin B sulfate and trimethoprim ophthalmic solution, USP)

    Sterile

    Polytrim Description

    Polytrim® (polymyxin B sulfate and trimethoprim ophthalmic solution, USP) is a sterile antimicrobial solution for topical ophthalmic use. It has pH of 4.0 to 6.2 and osmolality of 270 to 310 mOsm/kg.

    Chemical Names:

    Trimethoprim sulfate, 2,4-Diamino-5-(3,4,5-trimethoxybenzyl) pyrimidine sulfate, is a white, odorless, crystalline powder with a molecular weight of 678.72 and the following structural formula:

    Polymyxin B sulfate is the sulfate salt of polymyxin B1 and B2 which are produced by the growth of Bacillus polymyxa (Prazmowski) Migula (Fam. Bacillaceae). It has a potency of not less than 6,000 polymyxin B units per mg, calculated on an anhydrous basis. The structural formulae are:

    Contains: Actives: polymyxin B sulfate 10,000 units/mL; trimethoprim sulfate equivalent to 1 mg/mL. Preservative: benzalkonium chloride 0.04 mg/mL. Inactives: purified water; sodium chloride; and sulfuric acid. May also contain sodium hydroxide to adjust the pH.

    Polytrim - Clinical Pharmacology

    Trimethoprim is a synthetic antibacterial drug active against a wide variety of aerobic gram-positive and gram-negative ophthalmic pathogens. Trimethoprim blocks the production of tetrahydrofolic acid from dihydrofolic acid by binding to and reversibly inhibiting the enzyme dihydrofolate reductase. This binding is stronger for the bacterial enzyme than for the corresponding mammalian enzyme and therefore selectively i

    Pronunciation: pra-MOX-een/FEN-il-EF-rin/GLIS-er-in/PET-roe-LAY-tum
    Generic Name: Pramoxine/Phenylephrine/Glycerin/Petrolatum
    Brand Name: Preparation H Cream

    Pramoxine/Phenylephrine/Glycerin/Petrolatum is used for:

    Relieving pain, soreness, burning, itching, and discomfort of the anal area caused by hemorrhoids. It also temporarily shrinks hemorrhoidal tissue.

    Pramoxine/Phenylephrine/Glycerin/Petrolatum is a topical anesthetic, vasoconstrictor, and skin protectant. It works by blocking pain signals from the nerve endings in the skin and shrinking swollen tissue.

    Do NOT use Pramoxine/Phenylephrine/Glycerin/Petrolatum if:

    • you are allergic to any ingredient in Pramoxine/Phenylephrine/Glycerin/Petrolatum

    Contact your doctor or health care provider right away if any of these apply to you.

    Before using Pramoxine/Phenylephrine/Glycerin/Petrolatum:

    Some medical conditions may interact with Pramoxine/Phenylephrine/Glycerin/Petrolatum. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

    • if you are pregnant, planning to become pregnant, or are breast-feeding
    • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
    • if you have allergies to medicines, foods, or other substances
    • if you have heart problems, high blood pressure, thyroid problems, diabetes, or trouble urinating due to an enlarged prostate
    • if you are taking medicines for high blood pressure or depression

    Some MEDICINES MAY INTERACT with Pramoxine/Phe

    Pronunciation: POR-fi-mer
    Generic Name: Porfimer
    Brand Name: Photofrin

    Porfimer is used for:

    Relieving symptoms of some cancers and treating certain other cancers and tumors. It is used in combination with laser light therapy.

    Porfimer is an antineoplastic. It works by binding to cancer cells that are then exposed to laser light, which damages and sometimes kills the cancer cells.

    Do NOT use Porfimer if:

    • you are allergic to any ingredient in Porfimer
    • you have the blood disorder porphyria, an abnormal passage between the esophagus and trachea or windpipe, emergency breathing problems due to a bronchial lesion obstructing airflow, or a severe tumor involving a major blood vessel

    Contact your doctor or health care provider right away if any of these apply to you.

    Before using Porfimer:

    Some medical conditions may interact with Porfimer. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

    • if you are pregnant, planning to become pregnant, or are breast-feeding
    • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
    • if you have allergies to medicines, foods, or other substances

    Some MEDICINES MAY INTERACT with Porfimer. Tell your health care provider if you are taking any other medicines, especially any of the following:

    • Photosensitizing agents (eg, tetracyclines, sulfonamides, phenothiazines, certain blood glucose medicines, certain water pills, griseofulvin, fl
    Pronunciation: a-li-TREH-tih-no-in
    Generic Name: Alitretinoin
    Brand Name: Panretin

    Panretin is used for:

    Treating skin sores/lesions in patients with AIDS-related Kaposi sarcoma. It may also be used to treat other conditions as determined by your doctor.

    Panretin is a retinoid. It slows the growth of abnormal and normal skin cells. This slows or stops the growth of Kaposi sarcoma.

    Do NOT use Panretin if:

    • you are allergic to any ingredient in Panretin or to other retinoid medicines

    Contact your doctor or health care provider right away if any of this applies to you.

    Before using Panretin:

    Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

    • if you are pregnant, planning to become pregnant, or are breast-feeding
    • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
    • if you have allergies to medicines, foods, or other substances
    • if you have increased white blood cell counts, eczema, or lymphoma

    Some MEDICINES MAY INTERACT with Panretin. Tell your health care provider if you are taking any of the following medicines.

    • Tranexamic acid because side effects may be increased by Panretin.

    This may not be a complete list of all interactions that may occur. Ask your health care provider if Panretin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

    Generic Name: Pergolide Mesylate (PER-go-lide)
    Brand Name: Permax

    Pergolide Mesylate is used for:

    Treating Parkinson disease when used with levodopa/carbidopa.

    Pergolide Mesylate is dopamine agonist. It works by stimulating dopamine receptors in the brain.

    Do NOT use Pergolide Mesylate if:

    • you are allergic to any ingredient in Pergolide Mesylate
    • you are allergic to ergot-type medicines (eg, ergotamine)

    Contact your doctor or health care provider right away if any of these apply to you.

    Before using Pergolide Mesylate:

    Some medical conditions may interact with Pergolide Mesylate. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

    • if you are pregnant, planning to become pregnant, or are breast-feeding
    • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
    • if you have allergies to medicines, foods, or other substances
    • if you have a history of heart or kidney problems, irregular heartbeat, lung problems, low blood pressure, or hallucinations

    Some MEDICINES MAY INTERACT with Pergolide Mesylate. Tell your health care provider if you are taking any other medicines, especially any of the following:

    • Butyrophenones (eg, haloperidol), metoclopramide, phenothiazines (eg, thioridazine), or thioxanthenes (eg, thiothixene) because the effectiveness of Pergolide Mesylate may be decreased

    This may not be a complete list of all interact

    repaglinide
    Dosage Form: tablet
    Prandin® (repaglinide) Tablets (0.5, 1, and 2 mg)

    Prandin Description

    Prandin® (repaglinide) is an oral blood glucose-lowering drug of the meglitinide class used in the management of type 2 diabetes mellitus (also known as non-insulin dependent diabetes mellitus or NIDDM). Repaglinide, S(+)2-ethoxy-4(2((3-methyl-1-(2-(1-piperidinyl) phenyl)-butyl) amino)-2-oxoethyl) benzoic acid, is chemically unrelated to the oral sulfonylurea insulin secretagogues.

    The structural formula is as shown below:

    Repaglinide is a white to off-white powder with molecular formula C27 H36 N2 O4 and a molecular weight of 452.6. Prandin tablets contain 0.5 mg, 1 mg, or 2 mg of repaglinide. In addition each tablet contains the following inactive ingredients: calcium hydrogen phosphate (anhydrous), microcrystalline cellulose, maize starch, polacrilin potassium, povidone, glycerol (85%), magnesium stearate, meglumine, and poloxamer. The 1 mg and 2 mg tablets contain iron oxides (yellow and red, respectively) as coloring agents.

    Prandin - Clinical Pharmacology

    Mechanism of Action

    Repaglinide lowers blood glucose levels by stimulating the release of insulin from the pancreas. This action is dependent upon functioning beta (?) cells in the pancreatic islets. Insulin release is glucose-dependent and diminishes at low glucose concentrations.

    Repaglinide closes ATP-dependent potassium channels in the ?-cell membrane by binding at characterizable sites. This potassium channel blockade depolarizes

    Generic Name: mepivacaine (me PIV a kane)
    Brand Names: Carbocaine, Carbocaine HCl, Polocaine, Polocaine-MPF

    What is Polocaine-MPF (mepivacaine)?

    Mepivacaine is an anesthetic (numbing medicine) that blocks the nerve impulses that send pain signals to your brain.

    Mepivacaine is used as a local (in only one area) anesthetic for an epidural or spinal block. It is also used as an anesthetic for dental procedures.

    Mepivacaine may also be used for other purposes not listed in this medication guide.

    What is the most important information I should know about Polocaine-MPF (mepivacaine)?

    You should not receive mepivacaine if you have ever had an allergic reaction to any type of numbing medicine.

    Before receiving this medication, tell your doctor if you have liver disease, kidney disease, high or low blood pressure, asthma or a sulfite allergy, a history of heart disease or stroke, heart block or coronary artery disease, a heart rhythm disorder, or a thyroid disorder.

    This medication can cause numbness for an extended period of time. Avoid eating, chewing gum, or drinking hot liquids until the feeling in your mouth has returned completely. Chewing while your mouth is numb could result in a bite injury to your tongue, lips, or inside of your cheek.

    Spinal numbing medications can have long-lasting or permanent effects on certain body processes such as sexual function, bowel or bladder control, and movement or feeling in your legs or feet. Talk with your doctor about your specific risk of nerve damage from mepivacaine.

    What should I discuss with my health care provider before receiving Polocaine-MPF (mepivacaine)?

    You should not receive mepivacaine if you have ever had an allergic reaction to any type of numbing medicine.

    Before receiving mepivacaine, tell your doctor if you are allergic to any