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Class: Pituitary
VA Class: HS702
CAS Number: 11000-17-2
Brands: Pitressin

Introduction

Exogenous antidiuretic hormone (ADH); maintains serum osmolality in normal range and acts as a vasopressor.b 150 152 157

Uses for Vasopressin

Diabetes Insipidus

Prevention or control of polydypsia, polyuria, and dehydration in diabetes insipidus caused by a deficiency of endogenous posterior pituitary ADH (neurohypophyseal diabetes insipidus), but desmopressin usually considered drug of choice.b

May be used in the initial or emergency treatment of the disease, but, because of its short duration of action, its use is impractical for chronic therapy.154

Intranasal aqueous vasopressin may be effective for daily maintenance therapy and the degree of absorption is usually adequate to control mild diabetes insipidus; other drugs are preferred (e.g., chlorpropamide).154

Polyuria

May correct fluid imbalance associated with transient polyuria due to ADH deficiency accompanying neurosurgery or head injury.154

Not effective in controlling polyuria caused by renal disease, nephrogenic diabetes insipidus, hypokalemia or hypercalcemia, or polyuria secondary to the administration of demeclocycline or lithium carbonate.b

CPR

Used for its vasopressor effects; may give 1 dose to replace first or second dose of epinephrine in ACLS during CPR.150 152 153 157

Comparably effe

rimexolone
Dosage Form: ophthalmic suspension
Vexol® 1%
(rimexolone ophthalmic suspension)

DESCRIPTION

Vexol® 1% Ophthalmic Suspension is a sterile, multi-dose topical ophthalmic suspension containing the corticosteroid, rimexolone. Rimexolone is a white, water-insoluble powder with an empirical formula of C24H34O3 and a molecular weight of 370.53. Its chemical name is 11?-Hydroxy-16?,17?-dimethyl-17-propio nylandrosta-1,4-diene-3-one.The chemical structure of rimexolone is presented below:

Each mL Contains: Active ingredient: rimexolone 10 mg (1%). Preservative: benzalkonium chloride 0.01%. Inactive ingredients: carbomer 974P, polysorbate 80, sodium chloride, edetate disodium, sodium hydroxide and/or hydrochloric acid (to adjust pH) and purified water.

The pH of the suspension is 6.0 to 8.0 and the tonicity is 260 to 320 mOsmol/kg.

CLINICAL PHARMACOLOGY

Corticosteroids suppress the inflammatory response to a variety of inciting agents of a mechanical, chemical, or immunological nature. They inhibit edema, cellular infiltration, capillary dilatation, fibroblastic proliferation, deposition of collagen and scar formation associated with inflammation. Placebo-controlled clinical studies demonstrated that Vexol® 1% Ophthalmic Suspension is efficacious for the treatment of anterior chamber inflammation following cataract surgery.

In two controlled clinical trials, Vexol® 1% Ophthalmic Suspension demonstrated clinical equivalence to 1% prednisolone acetate in reducing uveitic inflammation. In a controlled 6-week study of steroid responsive subjects, the time to raise intraocular pressure was similar for Vexol® 1% Ophthalmic Suspension and 0.1% fluorometholone given

Generic Name: prenatal multivitamins (PRE nay tal VYE ta mins)
Brand Names: Advance Care Plus, Bright Beginnings, Cavan Folate, Cavan One, Cavan-Heme OB, Cenogen Ultra, CitraNatal Rx, Co Natal FA, Complete Natal DHA, Complete-RF, CompleteNate, Concept OB, Docosavit, Dualvit OB, Duet, Edge OB, Elite OB 400, Femecal OB, Folbecal, Folcaps Care One, Folivan-OB, Foltabs, Gesticare, Icar Prenatal, Icare Prenatal Rx, Inatal Advance, Infanate DHA, Kolnatal DHA, Lactocal-F, Marnatal-F, Maternity, Maxinate, Mission Prenatal, Multi-Nate 30, Multinatal Plus, Nata 29 Prenatal, Natachew, Natafort, Natelle, Neevo, Nestabs, Nexa Select with DHA, Novanatal, NovaStart, O-Cal Prenatal, OB Complete, OB Natal One, Ob-20, Obtrex DHA, OptiNate, Paire OB Plus DHA, PNV Select, PNV-Total, PR Natal 400, Pre-H-Cal, Precare, PreferaOB, Premesis Rx, PrenaCare, PrenaFirst, PrenaPlus, Prenatabs OBN, Prenatabs Rx, Prenatal 1 Plus 1, Prenatal Elite, Prenatal Multivitamins, Prenatal Plus, Prenatal S, Prenatal-U, Prenate Advanced Formula, Prenate DHA, Prenate Elite, Prenavite FC, PreNexa, PreQue 10, Previte Rx, PrimaCare, Pruet DHA, RE OB Plus DHA, Renate, RightStep, Rovin-NV, Se-Care, Se-Natal One, Se-Plete DHA, Se-Tan DHA, Select-OB, Seton ET, Strongstart, Stuart Prenatal with Beta Carotene, Tandem OB, Taron-BC, Tri Rx, TriAdvance, TriCare, Trimesis Rx, Trinate, Triveen-PRx RNF, UltimateCare Advance, Ultra-Natal, Vemavite PRX 2, VeNatal FA, Verotin-BY, Verotin-GR, Vinacal OR, Vinatal Forte, Vinate Advanced (New Formula), Vinate AZ, Vinate Care, Vinate Good Start, Vinate II (New Formula), Vinate III, Vinate One, Vitafol-OB, VitaNatal OB plus DHA, Vitaphil, Vitaphil Aide, Vitaphil Plus DHA, Vitaspire, Viva DHA, Vol-Nate, Vol-Plus, Vol-Tab Rx, Vynatal F.A., Zatean-CH, Zatean-PN

What are Vinate PN Care (prenatal multivitamins)?

There are many brands and forms of prenatal vitamin available and not all brands are listed on this leaflet.

Generic Name: lisdexamfetamine dimesylate (Oral route)

lis-dex-am-FET-a-meen dye-MES-i-late

Oral route(Capsule)

Amphetamines have a high potential for abuse, and administration for prolonged periods of time may lead to drug dependence and must be avoided. Misuse of amphetamines may cause sudden death and serious cardiovascular adverse events .

Commonly used brand name(s)

In the U.S.

  • Vyvanse

Available Dosage Forms:

  • Capsule

Therapeutic Class: CNS Stimulant

Chemical Class: Lisdexamfetamine

Uses For Vyvanse

Lisdexamfetamine dimesylate belongs to the group of medicines called central nervous system (CNS) stimulants. It is used to treat Attention deficit hyperactivity disorder (ADHD) in adults and children 6 years of age and older.

Lisdexamfetamine dimesylate increases attention and decreases restlessness in children and adults who are overactive, cannot concentrate for very long, or are easily distracted and impulsive. This medicine is used as part of a total treatment program that also includes social, educational, and psychological treatment.

This medicine is available only with your doctor's prescription.

Before Using Vyvanse

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your h

vax-IN-ee-a i-MUNE GLOB-ue-lin, HUE-man

Intravenous route(Solution)

Immune globulin intravenous (human) (IGIV) products have been reported to be associated with renal dysfunction, acute renal failure, osmotic nephrosis, proximal tubular nephropathy, and death. Use caution in patients predisposed to acute renal failure and administer at the minimum concentration available and the minimum rate of infusion practicable. Higher rates of renal failure were associated with IGIV products containing sucrose and administered at daily doses of 400 mg/kg or greater. Vaccinia immune globulin contains sucrose (5%) as a stabilizer, and the recommended dose is 100 mg/kg .

Commonly used brand name(s)

In the U.S.

  • Vaccinia Immune Globulin, Human

Available Dosage Forms:

  • Solution

Therapeutic Class: Immune Serum

Uses For vaccinia immune globulin, human

Vaccinia immune globulin is used to treat infections caused by the vaccinia virus.

Before Using vaccinia immune globulin, human

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For vaccinia immune globulin, human, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to vaccinia immune globulin, human or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Studies on vaccinia immune globulin, human have been done only in adult patients, and there is no known specific information comparing use of vaccinia immune globulin in children w

Generic Name: didanosine (Oral route)

dye-DAN-oh-seen

Oral route(Capsule, Delayed Release;Powder for Solution)

Fatal and nonfatal pancreatitis has occurred during therapy with didanosine. Didanosine should be suspended in patients with suspected pancreatitis and discontinued in patients with confirmed pancreatitis. Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported. Fatal lactic acidosis has been reported in pregnant women who received the combination of didanosine and stavudine with other antiretroviral agents. The combination of didanosine and stavudine should be used with caution during pregnancy and is recommended only if the potential benefit clearly outweighs the potential risk .

Commonly used brand name(s)

In the U.S.

  • Videx
  • Videx EC
  • Videx Pediatric

Available Dosage Forms:

  • Powder for Suspension
  • Tablet, Chewable
  • Powder for Solution
  • Capsule, Delayed Release

Therapeutic Class: Antiretroviral Agent

Pharmacologic Class: Nucleoside Reverse Transcriptase Inhibitor

Uses For Videx EC

Didanosine is used in combination with other medicines for the treatment of human immunodeficiency virus (HIV) infection. HIV is the virus that causes acquired immune deficiency syndrome (AIDS).

Didanosine will not cure or prevent HIV infection or AIDS. It helps keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay the development of problems usually related to AIDS or HIV disease. Didanosine will not keep you from spreading HIV to other people. People who receive this medicine may continue to have the problems usually related to AIDS or HIV disease.

This medicine is available only with your doctor's prescription.

The buff

Pronunciation: ne-VIR-a-peen
Generic Name: Nevirapine
Brand Name: Viramune

Severe and sometimes fatal liver problems have occurred in patients taking Viramune. This may occur in men and women, but the risk may be greater in women and in patients with a high CD4 cell count at the start of treatment. Certain pregnant women and women with a CD4 cell count higher than 250 have the greatest risk. Liver function tests and CD4 cell counts may be performed while you take Viramune. Contact your doctor right away if you develop a rash, dark urine, yellowing of the eyes or skin, pale stools, stomach pain, nausea, loss of appetite, or unusual tiredness.

Viramune should only be used in patients who have been diagnosed with HIV. Do not use Viramune to prevent HIV infection if you have been exposed to the virus.

Viramune may cause serious and sometimes fatal skin reactions. Contact your doctor immediately if you develop a rash or red, swollen, blistered, or peeling skin.

The risk of liver and skin problems is greatest during the first 18 weeks of therapy, but these problems may occur at any time during treatment. Your doctor will check for side effects frequently during the first several months after you start taking Viramune. Be sure to keep all doctor and lab appointments. Take Viramune exactly as prescribed by your doctor. If you develop a liver or skin problem or if you have a severe allergic reaction to Viramune, you must not take it again.


Viramune is used for:

Treating HIV infection. It must be used along with other HIV medicines.

Viramune is a nonnucleoside reverse transcriptase inhibitor (NNRTI). It works by blocking the growth of HIV.

Do NOT use Viramune if:

  • you are allergic to any ingredient in Viramune
Cephradine
Dosage Form: capsule, suspension

To reduce the development of drug-resistant bacteria and maintain the effectiveness of Velosef and other antibacterial drugs, Velosef should be used only to treat or prevent infections that are proven or strongly suspected to be caused by bacteria.

Velosef Description

Velosef (Cephradine) is a semisynthetic cephalosporin antibiotic; oral dosage forms include capsules containing 250 mg and 500 mg cephradine and cephradine for oral suspension containing, after constitution, 125 mg and 250 mg per 5 mL dose.

Cephradine is designated chemically as (6R, 7R) - 7 - [(R) - 2 - amino - 2 - (1,4 - cyclohexadien - 1 - yl)acetamido] - 3 - methyl - 8 - oxo - 5 - thia - 1 - azabicyclo[4.2.0]oct - 2 - ene - 2 - carboxylic acid. Structural formula:

Inactive ingredients: Velosef Capsules—colorants (D&C Red No. 33 and Yellow No. 10; FD&C Blue No. 1, and, for ‘250’ only, Red No. 3), gelatin, lactose, magnesium stearate, talc, and titanium dioxide. Velosef for Oral Suspension—citric acid, colorants (FD&C Red No. 40 for ‘250’ only; FD&C Yellow No. 6 for ‘125’ only), flavors, guar gum, methylcellulose, sodium citrate, and sucrose.

Velosef - Clinical Pharmacology

Velosef (Cephradine) is acid stable. It is rapidly absorbed after oral administration in the fasting state. Following single doses of 250 mg, 500 mg, and 1 g in normal adult volunteers, average peak serum concentrations within one hour were approximately 9 mcg/mL, 16.5 mcg/mL, and 24.2 mcg/mL, respectively. In vitro studies by an ultracentrifugation technique show that at therapeutic serum antibiotic concentrations, cephradine is minimally bound (8 to 17 percent) to normal serum protein. Cephr

Generic Name: estradiol (Transdermal route)

es-tra-DYE-ol

Transdermal route(Emulsion)

Estrogens increase the risk of endometrial cancer; monitor for abnormal vaginal bleeding. Estrogens with or without progestins should not be used for the prevention of cardiovascular disease or dementia. Increased risks of myocardial infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein thrombosis in postmenopausal women (50 to 79 years of age) have been reported. An increased risk of developing probable dementia in postmenopausal women 65 years of age or older has also been reported. Risks should be assumed to be similar for other doses, combinations, and dosage forms of estrogens and progestins. Estrogens, with or without progestins, should be prescribed at the lowest effective doses and for the shortest duration possible .

Transdermal route(Patch, Extended Release)

Estrogens increase the risk of endometrial cancer; monitor for abnormal vaginal bleeding. Estrogens with or without progestins should not be used for the prevention of cardiovascular disease or dementia. Increased risks of myocardial infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein thrombosis in postmenopausal women (50 to 79 years of age) have been reported. An increased risk of developing probable dementia in postmenopausal women 65 years of age or older has also been reported. Risks should be assumed to be similar for other doses, combinations, and dosage forms of estrogens and progestins. Estrogens, with or without progestins, should be prescribed at the lowest effective doses and for the shortest duration possible.

Transdermal route(Gel/Jelly)

Estrogens increase the risk of endometrial cancer; monitor for abnormal vaginal bleeding. Estrogens with or without progestins should not be used for the prevention of cardiovascular disease. Increased risks of myocardial infarction, stroke, in

Generic Name: barium sulfate (oral and rectal) (BER ee um SUL fate)
Brand Names: Anatrast, Bar-Test, Baricon, Baro-Cat, Barosperse, Bear-E-Yum GI, CheeTah, CheeTah Butterscotch, CheeTah Chocolaty-Fudge, CheeTah Orange, CheeTah Raspberry, Digibar 190, E-Z AC, E-Z Disk, E-Z Dose Kit with Polibar Plus, E-Z Paste, E-Z-Cat, E-Z-Cat Dry, E-Z-HD, E-Z-Paque, Enecat, Eneset 2, Enhancer, Entero VU, Entero-H, Entrobar, Esopho-Cat, Intropaste, Liqui-Coat HD, Liquid Barosperse, Liquid E-Z Paque, Liquid Polibar, Liquid Polibar Plus, Maxibar, Medebar Plus, Medebar Super 250, Polibar ACB, Readi-Cat, Readi-Cat 2, Scan C, Sitzmarks, Smoothie Readi-Cat 2, Sol-O-Pake, Tagitol V, Tonojug, Tonopaque, Varibar Honey, Varibar Nectar, Varibar Pudding, Varibar Thin, Varibar Thin Honey, Volumen

What is barium sulfate?

Barium sulfate is in a group of drugs called contrast agents. Barium sulfate works by coating the inside of your esophagus, stomach, or intestines which allows them to be seen more clearly on a CT scan or other radiologic (x-ray) examination.

Barium sulfate is used to help diagnose certain disorders of the esophagus, stomach, or intestines.

Barium sulfate may also be used for purposes not listed in this medication guide.

What is the most important information I should know about barium sulfate?

You should not use this medication if you are allergic to barium sulfate. Tell your doctor if you have ever had an allergic reaction to a contrast agent.

Before you use barium sulfate, tell your doctor if you have any allergies, or if you have asthma, cystic fibrosis, heart disease or high blood pressure, rectal cancer, a colostomy, a blockage in your stomach or intestines, a condition called pseudotumor cerebri, or if you have recently had a rectal biopsy or surgery on your esophagus, stomach, or intestines.

Tell your doctor if you are pregnant or b

Generic Name: estrogen (Vaginal route)

Commonly used brand name(s)

In the U.S.

  • Estrace
  • Estring
  • Femring
  • Ortho Dienestrol
  • Premarin
  • Vagifem

In Canada

  • Estragyn
  • Neo-Estrone
  • Oestrilin

Available Dosage Forms:

  • Tablet
  • Cream
  • Insert, Extended Release
  • Suppository

Uses For Vagifem

Estrogens are hormones produced by the body. Among other things, estrogens help develop and maintain female organs.

When your body is in short supply of this hormone, replacing it can ease the uncomfortable changes that occur in the vagina, vulva (female genitals), and urethra (part of the urinary system). Conditions that are treated with vaginal estrogens include a genital skin condition (vulvar atrophy), inflammation of the vagina (atrophic vaginitis), and inflammation of the urethra (atrophic urethritis).

Estrogens work partly by increasing a normal clear discharge from the vagina and making the vulva and urethra healthy. Using or applying an estrogen relieves or lessens:

  • Dryness and soreness in the vagina
  • Itching, redness, or soreness of the vulva
  • Feeling an urge to urinate more often then is needed or experiencing pain while urinating
  • Pain during sexual intercourse

When used vaginally or on the skin, most estrogens are absorbed into the bloodstream and cause some, but not all, of the same effects as when they are taken by mouth. Estrogens used vaginally at very low doses for treating local problems of the genitals and urinary system will not protect against osteoporosis or stop the hot flushes caused by menopause.

Estrogens for vaginal use are available only with your doctor's prescription.

Before Using Vagifem

Allergies

Tell yo

val-ay-SYE-kloe-vir

Commonly used brand name(s)

In the U.S.

  • Valtrex

Available Dosage Forms:

  • Tablet

Therapeutic Class: Antiviral

Pharmacologic Class: Viral DNA Polymerase Inhibitor

Chemical Class: Guanosine Nucleoside Analog

Uses For valacyclovir

Valacyclovir is used to treat herpes virus infections, including herpes labialis (also known as cold sores), herpes zoster (also known as shingles), and herpes simplex (also known as genital herpes) in adults. It is also used to treat chickenpox and cold sores in children.

In your body, valacyclovir becomes the anti-herpes medicine, acyclovir. Although valacyclovir will not cure shingles or genital herpes, it does help relieve the pain and discomfort and helps the sores heal faster.

Valacyclovir is available only with your doctor's prescription.

Before Using valacyclovir

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For valacyclovir, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to valacyclovir or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of valacyclovir in children below 12 years of age with cold sores, and children below 2 years of age with chickenpox. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limi

Generic Name: immune globulin (subcutaneous) (im MYOON GLOB yoo lin (sub koo TANE ee us))
Brand Names: Hizentra, Vivaglobin

What is immune globulin?

Immune globulin is a sterilized solution made from human plasma. It contains the antibodies to help your body protect itself against infection from various diseases.

Immune globulin subcutaneous (for injection under the skin) is used to treat primary immune deficiency.

Immune globulin may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about immune globulin?

You should not use this medication if you have ever had an allergic reaction to an immune globulin, if you have immune globulin A (IgA) deficiency with antibody to IgA, or if you have a condition called hyperprolinemia (high level of a certain amino acid in the blood).

Before using this medication, tell your doctor if you have blood circulation problems or a blood vessel disorder, a history of stroke or blood clot, or if you have been bed-ridden due to severe illness.

Immune globulin is usually given once every week. You may be shown how to use injections at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, tubing, and other items used to inject the medicine.

Subcutaneous immune globulin is for injection only under the skin. Do not inject this medicine into a vein.

If you use this medication at home, keep a diary of the days and times you used the medication and where you injected it on your body.

You may need a dose adjustment if you are exposed to measles, or if you travel to an area where this disease is common.

What should I discuss with my health care provider before using immune globulin?

You should not use this medication if you h
pindolol
Dosage Form: Tablets

T1999-39

89003701


   Visken®

   (pindolol)

   tablets, USP


   Rx only

Visken Description

Visken® (pindolol), a synthetic beta-adrenergic receptor blocking agent with intrinsic sympathomimetic activity is 1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol.


Its structural formula is:




Pindolol is a white to off-white odorless powder soluble in organic solvents and aqueous acids. Visken® (pindolol) is intended for oral administration.

5 mg and 10 mg Tablets

Active Ingredient: pindolol

Inactive Ingredients: colloidal silicon dioxide, magnesium stearate, microcrystalline cellulose, and pregelatinized starch.


Visken - Clinical Pharmacology

Visken® (pindolol) is a non-selective beta-adrenergic antagonist (beta-blocker) which possesses intrinsic sympathomimetic activity (ISA) in therapeutic dosage ranges but does not possess quinidine-like membrane stabilizing activity.

PHARMACODYNAMICS

In standard pharmacologic tests in man and animals, Visken® (pindolol) attenuates increases in heart rate, systolic blood pressure, and cardiac output resulting from exercise and isoproterenol administration, thus confirming its beta-blocking properties. The ISA or partial agonist activity of Visken® (pindolol) is mediated directly at the adrenergic receptor sites and may be blocked by other beta-blockers. In catecholamine-depleted animal experiments, ISA is manifested as an increase in the inotropic and chronotropic activity of the myocardium. In man, ISA is manifested by a smaller reduction in the resting heart rate (4-8 beats/min) than is

Generic Name: Tenofovir Disoproxil Fumarate
Class: Nucleoside and Nucleotide Reverse Transcriptase Inhibitors
VA Class: AM800
Chemical Name: Bis(1 - methyl - ethyl)ester - (R) - 5 - [[2 - (6 - Amino - 9H - purin - 9 - yl) - 1 - methylethoxy]methyl] - 2,4,6,8 - tetraoxa - 5 - phosphanonanedioic acid 5-oxide (E)-2-butenedioate
Molecular Formula: C9H14N5O4P•H2O
CAS Number: 202138-50-9

  • Lactic acidosis and severe hepatomegaly with steatosis (including some fatalities) reported rarely in patients receiving nucleoside reverse transcriptase inhibitors (NRTIs) alone or in conjunction with other antiretrovirals.1 7 (See Lactic Acidosis and Severe Hepatomegaly with Steatosis under Cautions.)

  • Severe acute exacerbations of hepatitis reported following discontinuance of tenofovir in patients with HBV infection.1 Monitor hepatic function closely with both clinical and laboratory follow-up for at least several months after tenofovir is discontinued.1 If appropriate, resumption of treatment for HBV infection may be warranted.1

Introduction

Antiretroviral with antiviral activity against hepatitis B virus (HBV); nucleotide reverse transcriptase inhibitor.1 2 3 5

Uses for Viread

Treatment of HIV Infection

Treatment of HIV-1 infection in conjunction with other antiretrovirals.1 6

For purposes of therapeutic decisions,

Generic Name: didanosine (Oral route)

dye-DAN-oh-seen

Oral route(Capsule, Delayed Release;Powder for Solution)

Fatal and nonfatal pancreatitis has occurred during therapy with didanosine. Didanosine should be suspended in patients with suspected pancreatitis and discontinued in patients with confirmed pancreatitis. Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported. Fatal lactic acidosis has been reported in pregnant women who received the combination of didanosine and stavudine with other antiretroviral agents. The combination of didanosine and stavudine should be used with caution during pregnancy and is recommended only if the potential benefit clearly outweighs the potential risk .

Commonly used brand name(s)

In the U.S.

  • Videx
  • Videx EC
  • Videx Pediatric

Available Dosage Forms:

  • Powder for Suspension
  • Tablet, Chewable
  • Powder for Solution
  • Capsule, Delayed Release

Therapeutic Class: Antiretroviral Agent

Pharmacologic Class: Nucleoside Reverse Transcriptase Inhibitor

Uses For Videx Pediatric

Didanosine is used in combination with other medicines for the treatment of human immunodeficiency virus (HIV) infection. HIV is the virus that causes acquired immune deficiency syndrome (AIDS).

Didanosine will not cure or prevent HIV infection or AIDS. It helps keep HIV from reproducing and appears to slow down the destruction of the immune system. This may help delay the development of problems usually related to AIDS or HIV disease. Didanosine will not keep you from spreading HIV to other people. People who receive this medicine may continue to have the problems usually related to AIDS or HIV disease.

This medicine is available only with your doctor's prescription.

The buffered t

Pronunciation: EYE-loe-prost
Generic Name: Iloprost
Brand Name: Ventavis

Ventavis is used for:

Treating high blood pressure in the pulmonary arteries of the lungs in patients with pulmonary arterial hypertension (PAH).

Ventavis is a form of prostacyclin. It is similar to a chemical in the body that widens (dilates) blood vessels, such as those in the arteries or lungs. Widening the blood vessels decreases high blood pressure.

Do NOT use Ventavis if:

  • you are allergic to any ingredient in Ventavis
  • you have certain lung problems (eg, chronic respiratory acidosis)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Ventavis:

Some medical conditions may interact with Ventavis. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have chronic obstructive pulmonary disease (COPD), severe asthma, or a lung infection
  • if you have liver or kidney problems, low blood pressure, or blood clotting problems

Some MEDICINES MAY INTERACT with Ventavis. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Anti
Pronunciation: ver-AP-a-mil
Generic Name: Verapamil
Brand Name: Calan

Verapamil Immediate-Release Tablets are used for:

Treating high blood pressure and chronic stable angina (chest pain). It may be used alone or with other medicines. It is also used for treating and preventing supraventricular tachycardia (a rhythm disturbance of the heart) and for controlling heart rate response to other rhythm disturbances, specifically atrial fibrillation and atrial flutter. It may also be used for other conditions as determined by your doctor.

Verapamil Immediate-Release Tablets are a calcium channel blocker. It works by relaxing (dilating) your blood vessels, lowering blood pressure, and decreasing heart rate, which lowers the workload on the heart. It also dilates coronary arteries, increasing blood flow to the heart. It also works by slowing the electrical conduction in the heart, slowing heart rate, and/or normalizing heart rhythm.

Do NOT use Verapamil Immediate-Release Tablets if:

  • you are allergic to any ingredient in Verapamil Immediate-Release Tablets
  • you have certain heart problems (eg, left ventricular dysfunction, sick sinus syndrome, second- or third-degree heart block and do not have a pacemaker), very low blood pressure, or moderate to severe congestive heart failure (CHF)
  • you have atrial fibrillation or flutter and a pre-excitation syndrome (extra conduction pathway in the heart), such as Wolff-Parkinson-White (WPW) syndrome or Lown-Ganong-Levine (LGL) syndrome
  • y
Pronunciation: TYE-oh-KON-a-zole
Generic Name: Tioconazole
Brand Name: Examples include Monistat-1 and Vagistat-1

Vagistat-1 is used for:

Treating vaginal yeast infections.

Vagistat-1 is an antifungal agent. It works by weakening the cell membrane of the fungus, resulting in the death of the fungus.

Do NOT use Vagistat-1 if:

  • you are allergic to any ingredient in Vagistat-1
  • you have never had a vaginal yeast infection diagnosed by a doctor
  • you have diabetes, a positive HIV test, or AIDS
  • you have stomach, back, or shoulder pain; fever (above 100 degrees F); chills; nausea; vomiting; foul-smelling vaginal discharge; or diarrhea

Contact your doctor or health care provider right away if any of these apply to you.

Before using Vagistat-1:

Some medical conditions may interact with Vagistat-1. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have been exposed to HIV
  • if this is the first time you have had vaginal itching and discomfort
  • if you have shoulder, stomach, or lower back pain; fever; chills; foul-smelling vaginal discharge; or nausea or vomiting
Pronunciation: a-SEET-a-MIN-oh-fen/AS-pir-in/KAF-een
Generic Name: Acetaminophen/Aspirin/Caffeine
Brand Name: Examples include Excedrin and Vanquish

Vanquish is used for:

Relieving headaches, migraine headaches, toothaches, muscle aches, premenstrual or menstrual aches, or other minor aches and pains (eg, due to sinusitis, arthritis, or colds). It may also be used for other conditions as determined by your doctor.

Vanquish is an analgesic and antipyretic combination. It works by blocking substances in the body that cause pain and inflammation.

Do NOT use Vanquish if:

  • you are allergic to any ingredient in Vanquish
  • you are a child or teenager with influenza (flu) or chickenpox
  • you have bleeding problems, such as hemophilia, von Willebrand disease, or low blood platelets
  • you have had a severe allergic reaction (eg, severe rash, hives, swelling of the face, breathing difficulties, dizziness) to aspirin, tartrazine, or a nonsteroidal anti-inflammatory drug (NSAID) (eg, celecoxib, ibuprofen, naproxen)
  • you are taking another medicine that contains acetaminophen

Contact your doctor or health care provider right away if any of these apply to you.

Before using Vanquish:

Some medical conditions may interact with Vanquish. Tell your health care provider if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation